- 【药物名称】Dimaprit
- 【化学名】1-(Amidinosulfanyl)-3-(dimethylamino)propane
- 【CAS登记号】
- 【结构式】
- 【分子式】C6-H15-N3-S
- 【分子量】161.2715
- 【原研厂家】
- 【作用类别】Histamine H2 Receptor Agonists, Nitric Oxide Synthase Inhibitors
- 【研发状态】Not Determined
- 【合成情况】
- 〖来源〗Drugs Fut
- 〖合成路线〗
- 〖标题〗Dimaprit
- 〖合成方法〗By condensation of 3-dimethylaminopropyl chloride (I) with thiourea (II) in refluxing ethanol.
- 〖作者〗Weetman, D.F.; Castaer, J.
- 〖参考〗Weetman, D.F.; Castaer, J.; Dimaprit. Drugs Fut 1978, 3, 4, 273
- 〖出处〗Drugs Fut1978,3,(4):273
- 〖备注〗Synthesis By condensation of 3-dimethylaminopropyl chloride (I) with thiourea (II) in refluxing ethanol (1). Description Dihydrochloride salt, m.p. 161-3?(1). Manufacturer Smith, Kline and French, Ltd., Welwyn Garden City (England) Reference 1. Kartinos, N.J. (Baxter Labs., Ltd.); US 3116327
- 〖来源〗US 3116327
- 〖合成路线〗
- 〖标题〗Gamma-Dimethylaminopropyl isothiourea and acid addition salts thereof
- 〖合成方法〗By condensation of 3-dimethylaminopropyl chloride (I) with thiourea (II) in refluxing ethanol.
- 〖作者〗Kartinos, N.J. (Baxter International Inc.)
- 〖参考〗Kartinos, N.J. (Baxter International Inc.); Gamma-Dimethylaminopropyl isothiourea and acid addition salts thereof. US 3116327
- 〖出处〗US 3116327,,():
- 〖备注〗
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