2 利法沙班乙酰杂质 1429334-00-8 (S)-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)propionamide
3 利法沙班中间体(http://www.chemdrug.com/sell/19/)3杂质 N/A (S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one
4 利法沙班草酰脲杂质 N/A 1,3-bis(((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)urea
5 利法沙班脱氯杂质 N/A (S)-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
6 利法沙班氮氧代杂质 446292-08-6 (S)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
7 氯噻吩-氨基-吗啉酮杂质 N/A (S)-1-amino-3-((4-(3-oxomorpholino)phenyl)amino)propan-2-yl 5-chlorothiophene-2-carboxylate
8 利法沙班3-氯杂质 N/A (S)-3-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
9 利法沙班4，5-二氯杂质 N/A (S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
10 利法沙班降解杂质 721401-53-2 (R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
11 利法沙班水解杂质 N/A (S)-2-(2-((4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic acid
12 利法沙班水解2杂质 N/A (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
13 利法沙班二胺1间苯甲酸杂质 N/A N1,N3-bis(((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isophthalamide
14 利法沙班三胺杂质 N/A 5-chloro-N-(4-((S)-5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
15 利法沙班二胺2杂质 NA N1,N2-bis(((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)phthalamide
16 利法沙班二胺3杂质 NA (S)-5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-(methylamino)-2-oxoethoxy)ethyl)thiophene-2-carboxamide
17 5-氯噻吩-2羧酸杂质 24065-33-6 5-chlorothiophene-2-carboxylic acid
18 4，5-二氯噻吩2-羧酸 NA 4,5-dichlorothiophene-2-carboxylic acid
19 噻吩2-羧酸杂质 NA thiophene-2-carboxylic acid
20 中间体1的R-异构体 NA (S)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione
21 中间体2的R-异构体 NA (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
22 中间体3的R-异构体 NA (R)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one
23 利法沙班杂质A NA ethyl (4-(3-oxomorpholino)phenyl)carbamate
24 利法沙班杂质B NA 2-methylisoindoline-1,3-dione
25 利法沙班杂质C NA (S)-N1-methyl-N2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)phthalamide
26 利法沙班杂质D R与S构型都有 2-(oxiran-2-yl)isoindoline-1,3-dione
27 利法沙班杂质E NA 4-(4-aminophenyl)morpholin-3-one
28 利法沙班杂质F NA methyl (4-(3-oxomorpholino)phenyl)carbamate
29 利法沙班杂质G NA 1-(4-(3-oxomorpholino)phenyl)-3-(4-(3-oxotetrahydro-2H-pyran-4-yl)phenyl)urea
30 利法沙班杂质H NA 3-chlorothiophene-2-carboxylic acid
31 利法沙班杂质I NA (S)-N1-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)phthalamide
32 利法沙班杂质J NA (S)-2-(((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoic acid
33 利法沙班杂质K NA 2-(2,3-dihydroxypropyl)isoindoline-1,3-dione
34 利法沙班杂质L NA 5-chloro-N-methylthiophene-2-carboxamide
35 利法沙班杂质M NA 4-(2-aminophenyl)morpholin-3-one
36 利法沙班杂质N NA 4-(2-nitrophenyl)morpholin-3-one
37 利法沙班杂质O NA 4-(4-nitrophenyl)morpholin-3-one
38 利法沙班杂质P NA 2-((4-nitrophenyl)amino)ethanol
39 利法沙班杂质Q NA 1-fluoro-4-nitrobenzene